Pharmacokinetic Herb-Drug Interactions: Are Preventive Screenings Necessary and Appropriate?
نویسندگان
چکیده
منابع مشابه
Herb-drug interactions.
Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors;...
متن کاملPharmacokinetic herb-drug interactions (part 2): drug interactions involving popular botanical dietary supplements and their clinical relevance.
In Part 2 of this review, a critical examination of the pertinent scientific literature is undertaken in order to assess the interaction risk that popular dietary supplements may pose when taken concomitantly with conventional medications. Botanicals most likely to produce clinically important herb-drug interactions are those whose phytochemicals act as mechanism-based inhibitors of cytochrome ...
متن کاملHerbal remedies: drug-herb interactions.
Controlled clinical studies are needed to clarify and determine the clinical importance of drug-herb interactions. However, it is unlikely that this information will be forthcoming except as anecdotal reports. Patients taking drugs with a narrow therapeutic index (cyclosporine, digoxin, hypoglycemic agents, lithium, phenytoin, procainamide, theophylline, tricyclic antidepressants, and warfarin)...
متن کاملCorrigendum: Herbal medicines in Brazil: pharmacokinetic profile and potential herb-drug interactions
[This corrects the article on p. 162 in vol. 5, PMID: 25071580.].
متن کاملHerbal medicines in Brazil: pharmacokinetic profile and potential herb-drug interactions
A plethora of active compounds found in herbal medicines can serve as substrate for enzymes involved in the metabolism of xenobiotics. When a medicinal plant is co-administered with a conventional drug and little or no information is known about the pharmacokinetics of the plant metabolites, there is an increased risk of potential herb-drug interactions. Moreover, genetic polymorphisms in a pop...
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ژورنال
عنوان ژورنال: Planta Medica
سال: 2004
ISSN: 0032-0943,1439-0221
DOI: 10.1055/s-2004-827223